The Colombian superstar was named as one of the first performers and will be alongside Andrea Bocelli and The Philadelphia Orchestra on September 26th in Philadelphia.
The event is expected to draw thousands during the Pope's visit to Philadelphia and millions will be watching the event live around the world. Pope Francis will also be going to New York and Washington, D.C.
"I am profoundly honored for the invitation to sing for the Pope Francisco. #ADiosLePido," Juanes tweeted following the announcement.
Juanes will perform for the Pope after his summer tour dates across Europe and the United States for his Loco De Amor Tour.
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