Trump comes roaring into the prime-time face-off at the University of Nevada, Las Vegas, claiming that the Clinton campaign, the media and the political establishment are conspiring to "rig" the election against him, using "false" stories from women who have accused him of sexual aggression.
"The media is trying to rig the election by giving credence, and this is so true, by giving credence to false stories that have no validity and making the front page," Trump said Monday in Green Bay, Wisconsin.
Clinton, meanwhile, is fighting off allegations associated with emails released by Wikileaks, including dealings between the campaign and Clinton Foundation donors. Trump and allies say the media are ignoring evidence of "pay-to-play" arrangements within Clinton's State Department and the Democratic nominee's tendency to say one thing in public and another in private.
Chris Wallace of Fox News will moderate the debate that starts at 9 p.m. Among the scheduled topics are debt and entitlements, immigration, economy, Supreme Court, "foreign hot spots" and "fitness to be president."
With Trump expected to attack Clinton, and vice versa, this confrontation figures to be a contrast to third debates of the past.